Development PipelineBrentuximab vedotin

an antibody–drug conjugate directed to CD30 being investigated in certain lymphomas and solid tumors

The safety and efficacy of these investigational compounds, or investigational uses of marketed products, have not been established. For an agent(s) whose safety and efficacy has not been established or confirmed, future regulatory approval or commercial availability is not guaranteed.

Clinical Trials

ECHELON-3: Diffuse large B-cell lymphoma

ClinicalTrials.Seagen.com ClinicalTrials.gov

  • Phase 1

  • Phase 2

  • Phase 3

CheckMate 744: AYA CD30+ Hodgkin lymphoma

ClinicalTrials.gov

  • Phase 1

  • Phase 2

  • Phase 3

SGN35-027: Early and advanced stage Hodgkin lymphoma

ClinicalTrials.Seagen.com ClinicalTrials.gov

  • Phase 1

  • Phase 2

  • Phase 3

SGN35-032: CD30-low and -negative peripheral T-cell lymphoma

ClinicalTrials.Seagen.com ClinicalTrials.gov

  • Phase 1

  • Phase 2

  • Phase 3

SGN35-033: Metastatic non-small cell lung cancer, melanoma, and squamous cell carcinoma of the head and neck

ClinicalTrials.Seagen.com ClinicalTrials.gov

  • Phase 1

  • Phase 2

  • Phase 3

Program Resources

High-level synopsis of brentuximab vedotin and ongoing clinical trials

Detailed information about brentuximab vedotin clinical trials

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Brentuximab Vedotin in Combination with Nivolumab Proposed Mechanism of Action